hrp0092p1-256 | Pituitary, Neuroendocrinology and Puberty (1) | ESPE2019

Kisspeptin Levels is a New Diagnostic Approach of Hypogonadotropic Hypogonadism in Boys

Nikitina Irina , Yukhlina Yulya , Nagornaya Irena , Kelmanson Igor , Grineva Elena

Background: In hypogonadotropic hypogonadism (HH), hypophyseal follicle-stimulating and luteinizing hormones, normally released with GnRH stimulation, are detected low. Since kisspeptin (KP) is a strong stimulant of GnRH neurons, it is considered to have a role in HH aetiology. It may be hypothesized that abnormal plasma levels of KP are indicative of HH.Aim: Evaluation and comparison of plasma KP levels in boys of pre-p...